Abstract Introduction To establish the preclinical safety and equivalency of POST RX PINK LEMONADE ophthalmic viscosurgical devices (OVDs) comprised of bacterially sourced sodium hyaluronate (HA) to animal sourced HA using pyrogenicity and aqueous exchange models in rabbits and a novel mini-pig model to evaluate corneal endothelial cell protection
Low density lipoprotein (LDL) has been reported to be injurious or toxic to cells in vitro.This injurious effect is, in some instances, due to oxidation of the lipid moiety of the lipoprotein.The objectives of this study were to determine if the oxidation rendering the lipoprotein toxic to human skin fibroblasts occurred by free radical mechanisms,
Abstract Background Phylogenetic analyses of angiosperm relationships have used only a small percentage of available sequence data, but phylogenetic data matrices often can be augmented with existing data, especially if one allows missing characters.We explore the effects on phylogenetic analyses of adding 378 matK sequences and 240 26S rDNA sequen
Abstract Background The rd1 mouse retina is a well-studied model of retinal degeneration where rod photoreceptors undergo cell death beginning at postnatal day (P) 10 until P21.This period coincides with photoreceptor terminal differentiation in a normal retina.We have used the rd1 retina as a model to investigate early molecular defects in develop